Abiraterone

-Delile

• Ngaphambi kokuthatha i-abiraterone,
• I-Abiraterone ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, shayela udokotela wakho ngokushesha:

I-Abiraterone isetshenziswa ngokuhlangana ne-prednisone ukwelapha uhlobo oluthile lomdlavuza wendlala yesinye eselusabalalele kwezinye izingxenye zomzimba. U-Abiraterone usesigabeni semithi ebizwa nge-androgen biosynthesis inhibitors. Isebenza ngokunciphisa inani lamahomoni athile emzimbeni.

I-Abiraterone iza njengethebhulethi ukuthatha ngomlomo esiswini esingenalutho ngamanzi, ihora eli-1 ngaphambi noma amahora amabili ngemuva kokudla noma yikuphi ukudla. Kuvame ukuthathwa kanye noma kabili ngosuku. Thatha i-abiraterone ngasikhathi sinye nsuku zonke. Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Thatha i-abiraterone njengoba nje iyalelwe. Ungayithathi kancane noma uyithathe kaningi kunokuyalelwa ngudokotela wakho.

Gwinya amaphilisi wonke ngamanzi; ungawahlukanisi, ungawahlafune noma uwagxoze.

Qhubeka uthathe i-abiraterone noma ngabe uzizwa uphilile. Ungayeki ukuthatha i-abiraterone noma i-prednisone ngaphandle kokukhuluma nodokotela wakho.

Buza usokhemisi noma udokotela wakho ikhophi lemininingwane yomkhiqizi yesiguli.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthatha i-abiraterone,

• Tshela udokotela wakho kanye nosokhemisi uma unegciwane ku-abiraterone, noma imiphi eminye imithi, noma iziphi izithako ezikumaphilisi e-abiraterone. Buza usokhemisi wakho ukuthola uhlu lwezithako.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi eminye imishanguzo kadokotela neyokungabhalisi, amavithamini, izithasiselo zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Qiniseka ukuthi usho noma ikuphi kokulandelayo: dextromethorphan; imithi ethile yokuquleka efana ne-carbamazepine (Carbatrol, Epitol, Tegretol), phenobarbital, ne-phenytoin (Dilantin, Phenytek); ketoconazole; nefazodone; i-pioglitazone (Actos); i-rifabutin (i-Mycobutin); i-rifampin (iRifadin, eRifamate, eRifater, eRimactane); i-rifapentine (Priftin); futhi thioridazine. Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi. Eminye imishanguzo eminingi ingaxhumana ne-abiraterone, ngakho-ke qiniseka ukuthi utshela udokotela wakho ngayo yonke imithi oyiphuzayo, ngisho naleyo engabonakali kulolu hlu.
• Tshela udokotela wakho uma unesifo, izinga eliphansi le-potassium egazini lakho, noma uhlangabezana nokucindezeleka okungavamile, uke wahlaselwa yinhliziyo muva nje, noma uma uke waba nezinkinga ze-adrenal noma i-pituitary gland, ukwehluleka kwenhliziyo, okungajwayelekile ukushaya kwenhliziyo, kufaka phakathi ukwandiswa kwe-QT (isigqi senhliziyo esingajwayelekile esingaholela ekuphelelweni amandla, ekulahlekelweni ukwazi, ekuqulekeni, noma ekufeni okungazelelwe), umfutho wegazi ophakeme, noma isifo senhliziyo noma sesibindi.
• kufanele wazi ukuthi i-abiraterone isetshenziselwa amadoda kuphela. Abesifazane akufanele bathathe le mithi, ikakhulukazi uma bekhulelwe noma bengakhulelwa noma bencelisa. Uma ithathwa ngabesifazane abakhulelwe, i-abiraterone ingalimaza umbungu. Abesifazane abakhona, abangakhulelwa, noma abakhulelwe akufanele bathinte amaphilisi e-abiraterone ngaphandle kwamagilavu ​​okuvikela. Uma owesifazane okhulelwe ephuza noma ethinta amaphilisi e-abiraterone, kufanele abize udokotela wakhe ngokushesha.
• abesilisa abanomlingani wesifazane othatha i-abiraterone kumele basebenzise izindlela zokuvimbela inzalo ezisebenzayo ngesikhathi sokwelashwa kanye namaviki amathathu ngemuva komthamo wokugcina. Khuluma nodokotela wakho ngezinhlobo zokulawulwa kokuzalwa okulungele wena.
• kufanele wazi ukuthi lo muthi unganciphisa ukuzala emadodeni. Khuluma nodokotela wakho ngezingozi zokuthatha i-abiraterone.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.

Uma uphuthelwa umthamo owodwa, thatha umthamo wakho ojwayelekile ngosuku olulandelayo. Uma uphuthelwa umthamo ongaphezu kowodwa, shayela udokotela wakho khona manjalo.

I-Abiraterone ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• ukuvuvukala okuhlangene noma ubuhlungu
• ubuhlungu be-groin
• ukushisa okushisayo (ukuqhuma okungazelelwe kokushisa komzimba okuncane noma okukhulu)
• isifo sohudo
• isilungulela
• ukukhwehlela
• ubunzima bokulala noma ukulala

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, shayela udokotela wakho ngokushesha:

• isiyezi
• ukuzizwa uphela amandla noma unekhanda elincane
• ikhanda
• ukudideka
• ukushaya kwenhliziyo okusheshayo noma okungajwayelekile
• ubuthakathaka bemisipha noma ubuhlungu
• ubuhlungu bomlenze
• ukuvuvukala kwezandla, izinyawo, amaqakala, noma imilenze engezansi
• ukuqubuka
• ukulimaza noma ukopha okungavamile
• ukukhathala ngokweqile
• ukungabi namandla
• isicanucanu
• ukuhlanza
• ukulahlekelwa isifiso sokudla
• ubuhlungu engxenyeni engenhla kwesokudla yesisu
• ukuphuzi kwesikhumba noma kwamehlo
• izimpawu ezinjengomkhuhlane
• igazi emchameni
• ukuchama okunzima, okubuhlungu, noma okuvamile
• ukuphuka kwamathambo

I-Abiraterone ingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthatha lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Gcina le mithi esitsheni efike ngayo, ivalwe ngokuqinile, futhi lapho izingane zingafinyeleleki khona. Gcina ekamelweni lokushisa futhi kude nokushisa okweqile nomswakama (hhayi endlini yangasese).

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Umfutho wegazi lakho kufanele uhlolwe njalo. Udokotela wakho uzo-oda izivivinyo ezithile zelebhu ukuze ahlole impendulo yomzimba wakho ku-abiraterone.

Ungavumeli omunye umuntu ukuthi athathe imithi yakho. Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana nokugcwalisa umuthi wakho.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• Zytiga^®