I-Mercaptopurine

-Delile

• Ngaphambi kokuthatha i-mercaptopurine,
• IMercaptopurine ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, shayela udokotela wakho ngokushesha:
• Izimpawu zokudlula ngokweqile zingafaka:

IMercaptopurine isetshenziswa yodwa noma neminye imishanguzo yokwelapha ngamakhemikhali ukwelapha i-acute lymphocytic leukemia (BONKE; ebizwa nangokuthi i-acute lymphoblastic leukemia ne-acute lymphatic leukemia; uhlobo lomdlavuza oqala kumaseli amhlophe egazi). IMercaptopurine isekilasini lemithi ebizwa ngabaphikisi be-purine. Isebenza ngokumisa ukukhula kwamangqamuzana omdlavuza.

IMercaptopurine iza njengethebhulethi kanye nokumiswa (uketshezi) ukuthatha ngomlomo. Kuvame ukuthathwa kanye ngosuku. Thatha i-mercaptopurine ngasikhathi sinye nsuku zonke. Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Thatha i-mercaptopurine njengoba nje uqondisiwe. Ungayithathi kancane noma uyithathe kaningi kunokuyalelwa ngudokotela wakho.

Uma uthatha ukumiswa, yinyakazise kahle ibhodlela imizuzwana engama-30 ngaphambi kokusetshenziswa ngakunye ukuxuba umuthi ngokulinganayo. Kubalulekile ukusebenzisa isirinji yomlomo (ithuluzi lokulinganisa) ukukala ngokunembile futhi uthathe umthamo wakho we-mercaptopurine. Uma ungasitholi isirinji yomlomo ngemithi yakho, cela usokhemisi wakho ukuthi akunikeze. Ngemuva kokusebenzisa isirinji yomlomo ukuthatha imishanguzo yakho, susa i-plunger kuyo yonke into yokulinganisa, ugeze zombili izingxenye ngamanzi afudumele anensipho, bese ugeza ngaphansi kwamanzi ompompi ahambayo. Vumela izingxenye ukuthi zome ngaphambi kokuphindisela ukusebenziseka okulandelayo.

Qhubeka uthathe i-mercaptopurine noma ngabe uzizwa uphilile. Ungayeki ukuthatha i-mercaptopurine ngaphandle kokukhuluma nodokotela wakho

I-Mercaptopurine kwesinye isikhathi isetshenziselwa ukwelapha ezinye izinhlobo zomdlavuza, isifo sikaCrohn (isimo lapho umzimba uhlasela ulwelwesi lomgudu wokugaya ukudla obangela ubuhlungu, isifo sohudo, ukwehla kwesisindo, nomkhuhlane), kanye ne-ulcerative colitis. emathunjini abangela ubuhlungu nohudo). Khuluma nodokotela wakho mayelana nezingozi zokusebenzisa lo muthi ngesimo sakho.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthatha i-mercaptopurine,

• Tshela udokotela wakho kanye nosokhemisi uma unegciwane ku-mercaptopurine, noma imuphi omunye umuthi, noma iziphi izithako ezikumaphilisi e-mercaptopurine noma ukumiswa. Buza usokhemisi wakho ukuthola uhlu lwezithako.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi imishanguzo kadokotela neyokungabhalisi, amavithamini, izithako zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Qiniseka ukuthi usho noma yikuphi okulandelayo: allopurinol (Lopurin, Zyloprim); ama-aminosalicylates afana ne-mesalamine (Apriso, Asacol, Canasa, Lialda, Delzicol, Pentasa, abanye), olsalazine (Dipentum), ne-sulfasalazine (Azulfidine); ama-anticoagulants (’ama-thinner egazi’) njenge-warfarin (i-Coumadin, i-Jantoven); i-doxorubicin (Doxil); kanye ne-trimethoprim ne-sulfamethoxazole (Bactrim, Septra). Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi.
• Tshela udokotela wakho uma usuvele uthathe i-mercaptopurine noma i-thioguanine ukwelapha umdlavuza wakho.Udokotela wakho angakutshela ukuthi ungathathi i-mercaptopurine uma enye yale mithi ingasebenzanga kahle ekulweni nomdlavuza wakho esikhathini esedlule.
• Tshela udokotela wakho uma unanoma yiluphi uhlobo lokutheleleka futhi uma uke waba nesifo sesibindi noma sezinso.
• tshela udokotela wakho uma ukhulelwe, hlela ukukhulelwa, noma uncelisa. Kufanele usebenzise ukulawulwa kokuzalwa ukugwema ukukhulelwa ngesikhathi sokwelashwa kwakho nge-mercaptopurine. Uma ukhulelwa ngenkathi uthatha i-mercaptopurine, shayela udokotela wakho ngokushesha. IMercaptopurine ingalimaza umbungu.
• uma uhlinzwa, kufaka phakathi ukuhlinzwa kwamazinyo, tshela udokotela noma udokotela wamazinyo ukuthi uthatha i-mercaptopurine.
• ungenayo imigomo ngaphandle kokukhuluma nodokotela wakho.
• kufanele wazi ukuthi ubungozi bokuthi uzoba nemiphumela emibi kakhulu ye-mercaptopurine bungaba bukhulu uma unesici sofuzo (esizuzwe njengefa). Udokotela wakho angalawula ukuhlolwa ngaphambi noma ngesikhathi sokwelashwa kwakho ukuze abone ukuthi unale nto engcupheni.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.

Thatha umthamo ongabanjwanga ngokushesha nje lapho uwukhumbula. Kodwa-ke, uma sekuyisikhathi somthamo olandelayo, weqa umthamo ongabanjwanga bese uqhubeka neshejuli yakho ejwayelekile yokulinganisa. Ungathathi umthamo ophindwe kabili ukwenza okulahlekile.

IMercaptopurine ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• isicanucanu
• ukuhlanza
• ukufiphaza kwesikhumba
• ukulahleka kwezinwele
• ukuqubuka

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, shayela udokotela wakho ngokushesha:

• isikhumba esiphaphathekile
• ubuthakathaka
• ukuphelelwa umoya
• umphimbo obuhlungu, umkhuhlane, ukubanda, noma ezinye izimpawu zokutheleleka
• ukuvuvukala emilenzeni, emaqakaleni, noma ezinyaweni
• ukulimaza noma ukopha okungavamile
• ukuphuzi kwesikhumba noma kwamehlo
• ukulahlekelwa isifiso sokudla
• isifo sohudo
• ukuvuvukala kwendawo yesisu
• ubuhlungu engxenyeni engenhla kwesokudla yesisu

Ukuthatha i-mercaptopurine kungakhuphula ubungozi bokuthi uzoba nomdlavuza omusha. Abanye abantu abathathe i-mercaptopurine ukwelapha isifo sikaCrohn noma i-ulcerative colitis baba ne-hepatosplenic T cell lymphoma (HSTCL), uhlobo lomdlavuza olubi kakhulu oluvame ukubulala esikhathini esifushane. Tshela udokotela wakho uma uhlangabezana nalezi zimpawu ezilandelayo: ubuhlungu besisu; imfiva; ukuncipha kwesisindo okungaqondakali; ukujuluka ebusuku noma ukulimaza okulula noma ukopha. Khuluma nodokotela wakho ngezingozi zokuthatha lo muthi.

IMercaptopurine ingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthatha lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Gcina le mithi esitsheni efike ngayo, ivalwe ngokuqinile, futhi lapho izingane zingafinyeleleki khona. Gcina ekamelweni lokushisa futhi kude nokushisa okweqile nomswakama (hhayi endlini yangasese). Ukumiswa kweMercaptopurine kungagcinwa ekamelweni lokushisa kuze kube amasonto ayisithupha ngemuva kokuba ibhodlela livulwe okokuqala. Bese ulahla noma ikuphi ukumiswa okusele ngemuva kwamasonto ayisithupha.

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Izimpawu zokudlula ngokweqile zingafaka:

• ukulahlekelwa isifiso sokudla
• isicanucanu
• ukuhlanza
• isifo sohudo
• isikhumba esiphaphathekile
• ubuthakathaka
• ukuphelelwa umoya
• umphimbo obuhlungu, umkhuhlane, amakhaza nezinye izimpawu zokutheleleka
• ukulimaza noma ukopha okungavamile

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho uzo-oda izivivinyo ezithile zelebhu ukuze ahlole impendulo yomzimba wakho ku-mercaptopurine.

Ungavumeli omunye umuntu ukuthi athathe imithi yakho. Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana nokugcwalisa umuthi wakho.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

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• 6-MP